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It demonstrated that longer-acting GLP-1 analogs could be even better since exenatide was short-acting, the obvious next step was to extend its action to once-daily or once-weekly to provide more consistent glucose control
Current laboratory, animal, and early clinical research is encouraging and has not identified a consistent pattern of serious adverse events
Ler Artigo Xie, Y., Choi, T., & Al-Aly, Z
Updated 25 August 2017
The R311C mutation results in a catastrophic loss-of-function as it destabilises key electrostatic interactions within the catalytic site that are essential for CaMKK2 activity [144]
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